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Creatine is one of the few supplements I actually notice a difference if I quit taking. Happy to see it’s benefits extend to beyond performance in the gym.


Funny because I'm not sure I quite notice it immediately when I stop taking it, presumably since the body retains a certain amount of it. But I definitely notice a difference when taking it the first day after not having had it a little while, especially when taking 20+ grams a day. It gives me so much mental energy and alertness that I won't get a whole lot of sleep, but the next day I end up feeling just fine. If I remember correctly, there have been at least 2 studies that suggested high doses of creatine reduce the side effects of suboptimal sleep, and that definitely seems to be the case in my experience.


Isn't 20+ grams a day a lot for the kidneys? genuine question


Elevated creatinine levels (in absence of supplementation) is a sign of kidney issues. There are many studies showing no reverse link i.e. supplementing creatine damaging kidneys

https://link.springer.com/content/pdf/10.1186/s12882-025-045...


Okay but logically kidney issues leading to high creatine does suggest that creatine is not all that good for the body, no? else why would the kidney keep it under control?


Would you suggest that white blood cells are "not all that good for the body" because they're amped up during a bout of sickness?

Maybe they aren't! But you can't infer that from the mere correlation. Hence that phrase about its relationship to causation.


No, elevated creatinine levels is only a sign of kidney disease if all else remains equal. Consuming more creatine will naturally increase production of creatinine because creatinine is a byproduct of the kidneys processing creatine.

In other words, it's not a very reliable signal for kidney disease. There is a more reliable blood test called a "Cystatin C" test.


Not the parent, but someone else commented on this: https://news.ycombinator.com/item?id=48347735


I feel like it makes me feel like crap and my brain weird every time I try it and searching my spreadsheet shows this effect many times when I forget and read something like the above article and try it again. Anyone else feel like this?


Are you increasing your water intake when you do? That sounds like dehydration. Creatine takes a large amount of water to appropriately process, and during the loading phase, your body is pushing substantially more water into your muscles. Anecdotally, if I don't drink something like an extra half gallon of water a day while loading at 15g/day, I show symptoms of dehydration. And I'm already drinking somewhere between a half gallon to a gallon a day.


I think I do but I guess I could try.


Something to add to the spreadsheet :)


Yes I can definitely “feel” it when I take it, especially so at 10g+. And it makes me overly reactive and somewhat irritable, and gives me a ton of energy that needs to be let out lest the former two get worse.


> searching my spreadsheet

What does this mean?


I keep a spreadsheet about my health, blood work, any supplements I take, how they make me feel etc. The summary would be that I take zero supplements now haha. I have tried so so many.


Any chance you'd be willing to share a template of your spreadsheet?


They likely keep a journal of their mental state in a spreadsheet? Generally a good idea


The only thing I notice is the impact to my weight. I think it makes me marginally stronger but not a huge effect. I take it because research seems to indicate it's a net positive with a small effect and it seems very safe...


What sort of differences beyond gym related?


After 10g or so, the excess starts going to the brain which helps quite a bit with brain energy.


What exactly does it do? What is brain energy?


A good question, but we don't know what anti-depressants do or how they do it, same with anti-psychotics, mood stabilizers, psychedelics, etc. I think we can say we have good theories for creatine.

We do know that it does do something at certain doses.


There are lots of studies. It's possible to find satisfactory information. Creatine has been studied for a very long time.

First hand experience for many is a noticeable improvement, especially during busy/sleep minimizing times, to the point where it can sometimes be a substitute for caffiene without the crash.



> no significant skin effect at 400Hz -> use speaker wire, lol

now run that unshielded wire 50 meters past racks of GPUs and enjoy your EMI

> The 400Hz distribution industry is massive; the entire aerospace industry runs on it

nothing in that catalog is rated for 100kW–1MW rack loads at 800Vrms

> 3 phase @ 400Hz is x6 = 2.4kHz... Your PSU is now 14 diodes and a ceramic cap

you still need an inverter-based UPS upstream, which is the exact conversion stage DC eliminates

> large voltage/current DC breakers are.. gnarly, and expensive. DC does not like to stop flowing

SiC solid-state DC breakers are shipping today from every major vendor

> DC-DC converters are great, but you're not going to beat a transformer in efficiency or reliability

wide-bandgap converters are at 95%+ with no moving parts


"now run that unshielded wire 50 meters past racks of GPUs and enjoy your EMI"

Multipole expansion scales faster than r^2.

Also, im not in the field (clearly) but GPUs cant handle 2.4 kHz? The quarter wavelength is 30km.

"nothing in that catalog is rated for 100kW–1MW rack loads at 800Vrms"

Current wise, the catalog covers this track just fine. As to the voltages, well that's the whole point of AC! The voltage you need is but a few loops of wire away.

"you still need an inverter-based UPS upstream, which is the exact conversion stage DC eliminates"

So keep it? To clarify, this is the "we're too good for plebeian power, so we'll transform it AC->DC->AC", right?

"SiC solid-state DC breakers are shipping today from every major vendor"

Of course they do. They're also pricey, have limited current capability (both capital costs and therefore irrelevant when the industry is awash with GCC money) and lower conduction, and therefore higher heat.

They're really nice though.

"wide-bandgap converters are at 95%+ with no moving parts"

transformers have no moving parts. Loaded they can do 97%+ efficiency, or 2MW of heat eliminated on a 100MW center.


Rich!= smart


> Having to work in an office for $300k/year

More like $98k/year on average


As a senior person at AWS? Even so, that's more than most engineers earn at the end of their career here.


How "distasteful."


My 2023 Chevy Bolt EUV does exactly this with SuperCruise, in layers. Look away from the road for a few seconds? Visible warning. Keep looking away? Audible warning. Still looking away? SuperCruise disables, slows the vehicle to a stop, and calls OnStar.


and no moving internal parts + mostly sealed from dust. I'll do the same with mine.


Fwiw my 2012 mbp still runs. Takes in plenty of dust working outside and on account of the plastic hinge turning brittle and falling apart years ago. Once every two years I will open her up and blow her clean again. Thats about all the maintenance she needs today. Ironically it has somewhat stronger specs than gps new m1 air, considering I also have 16gb memory, but then 1.5tb of storage and 2 operating systems.


I'm not even sure the first part is. I logged into a Guest Account on my Mac and the default for 'New tabs open with:' is the 'Start Page', which is a blank page with history, bookmarks, frequently visited, etc.


Add my vote as a satisfied user. The M1 Air is the best personal laptop I've ever used. The battery life is just impeccable, it has plenty of power for what I need, and I imagine the longevity of this thing will be great because of the lack of fan and entry points for dust.



Scrum masters shouldn't be contributing ideas in terms of implementation or design unless they're also part of the dev team. They're there to facilitate. Product owners are probably more akin to "idea guys".

Edit: Even product owner is a bit of a stretch on my part. They're presenting user stories and requirements, which the dev team can pick and choose from the backlog (which, albeit, is prioritized by the product owner).


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